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35岁以下年轻宫颈癌患者临床病理特征及预后分析 被引量:36

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摘要 目的探讨35岁以下年轻宫颈癌的临床病理特征以及相关治疗和预后。方法回顾性分析收治的35岁以下年轻宫颈癌患者的临床病理资料,对其预后情况进行随访。结果 35岁以下年轻宫颈癌患者以低分化鳞癌居多,FIGO早期患者中,非鳞癌生存率低于鳞癌(P=0.024)。伴有术后高危病理因素的患者生存率均短于不伴有术后高危病理因素患者(P<0.05)。多因素分析发现病理类型、淋巴结转移情况在一定程度上与年轻宫颈癌患者的预后密切相关(P<0.05)。结论非鳞癌病理类型增加淋巴结转移的风险,伴有术后高危病理因素的患者(尤其是淋巴结转移阳性)应积极予以辅助治疗和严密随访,对提高患者的生活质量、改善预后以及降低病死率都有着重要的意义。
出处 《广东医学》 CAS CSCD 北大核心 2012年第18期2802-2804,共3页 Guangdong Medical Journal
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参考文献13

  • 1JEMAL A, SIEGEL R, WARD E, et al. Cancer statistics, 2007 [J]. CA Cancer J Clin, 2007, 57(1) : 43 -66.
  • 2KAMANGAR F, DORES G M, ANDERSON W F. Patterns of cancer incidence, mortality, and prevalence across five continents : defining priorities to reduce cancer disparities in different geo- graphic regions of the world [ J ]. J Clin Oncol, 2006, 24 (14) : 2137 - 2150.
  • 3DELALOYE J F, PAMPALLONA S, COUCKE P A, et al. Youn- ger age as a bad prognostic factor in patients with carcinoma of the cervix[J]. Eur J Obstet Gynecol Reprod Biol, 1996, 64(2): 201 - 205.
  • 4刘兰芳,孙海燕.831例35岁以下妇女宫颈癌的临床病理特点和预后[J].中国癌症杂志,2008,18(4):298-301. 被引量:37
  • 5石琪,王平.60例年轻妇女宫颈癌临床病理分析[J].四川大学学报(医学版),2005,36(5):754-755. 被引量:2
  • 6MASUMOTO N, FUJII T, ISHIKAWA M, et al. Dominant human papillomavirus 16 infection in cervical neoplasia in young Japanese women; study of 881 outpatients[J]. Gynecol Oncol, 2004, 94 (2) : 509 -514.
  • 7WAGGONER S E, DARCY K M, TIAN C, et al. Smoking beha- vior in women with locally advanced cervical carcinoma: a Gyneco- logic Oncology Group study[ J]. Am J Obstet Gynecol, 2010, 202 (3) : 283,e1-e7.
  • 8WOODMAN C B, COLLINS S, WINTER H, et al. Natural history of cervical human papillomavirus infection in young women: longitu- dinal cohort study[ J]. Lancet, 2001,357 (9271) :1831 - 1836.
  • 9MOKTAR A, RAVOORI S, VADHANAM M V, et al. Cigarette smoke - induced DNA damage and repair detected hy the comet as- say in HPV - transformed cervical cells [ J ]. Int J Oncol, 2009, 35(6) : 1297 -1304.
  • 10SCHORGE J O, KNOWLES L M, LEA J S. Adenocarcinoma of the cervix[J]. Curr Treat Options Oncol, 2004, 5(2) :119 -127.

二级参考文献20

  • 1廖秦平.宫颈癌病因学研究新进展[J].中国妇产科临床杂志,2003,4(4):243-245. 被引量:55
  • 2程晶,陈惠祯,吴绪峰,刘诗杈,胡继媛.腹膜外卵巢移位术在子宫颈癌治疗中的应用[J].中华妇产科杂志,1993,28(9):542-544. 被引量:15
  • 3Josefsson AM,Magnusson PK, Ylitalo N, et al. Viral load of human papilloma virus 16 as a determinant for development of cervical carcinoma in situ: a nested case-control study. Lancet,2000;355(9222):2189.
  • 4Morice P,Castaigne D,Haie-Meder C, et al. Laparoscopic ovarian transposition for pelvic malignancies: indication and functional outcomes. Fertil Steril,1998;70:956.
  • 5Paraskevaidis E, Kalantaridou SN, Kaponis A ,et al. Surgical management of early stage cervical cancer: ten years experience from one Greek health region. Eur J Gynaecol-Oncol,2002,23(4):341.
  • 6Bulk S, Visser O, Rozendaal L, et al . Cervical cancer in the Netherlands 1989-1998:decrease of squamous cell carcinoma in older women, increase of adenocarcinoma in younger women [ J ]. Cancer 2005,113 ( 6 ) : 1005-1009.
  • 7Acharki A, Sahraoui S, Benider A, et al. Cancer of the uterine cervix in young women: a retrospective study of 337 cases [ J ]. Bull Cancer, 1997 , 84 ( 4 ) : 373-378.
  • 8Ho CM, Chien TY, Huang SH, et al. Multivariate analysis of the prognostic factors and outcomes in early cervical cancer patients undergoing radical hysterectomy [ J ]. Gynecol Oncol, 2004 , 93 ( 2 ) :458-464.
  • 9Marchiole P, Buenerd A, Benchaib M, et al Clinical significance of lympho vascular space involvement and lymph node micrometastases in early-stage cervical cancer: a retrospective case-control surgical-pathological study [ J ]. Gynecol Oncol, 2005 , 97 (3) :725-6.
  • 10Clark MA, Nahas W, Mardert RT et al. Cervical cancer: women aged 35 and younger compared aged 36 and older [ J ]. Am Clin Oncol, 1991,14 (2) :352-356.

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