摘要
目的:探讨孕28～33+6周胎膜早破(PROM)期待治疗时间对妊娠结局的影响。方法:回顾性分析103例孕28～33+6周PROM孕妇的临床资料。按孕周分为孕28～31+6周45例和孕32～33+6周58例。按期待治疗时间长短分为两个亚组:A组期待治疗时间<3 d;B组期待治疗时间≥3 d。比较各组孕产妇及早产儿并发症差异。结果:①孕28～31+6周PPROM组新生儿窒息率、新生儿呼吸窘迫综合征(NRDS)发生率和早产儿病死率及孕产妇宫内感染率均高于孕32～33+6周组,差异有统计学意义(P<0.05)。②孕28～31+6周A组早产儿病死率高于B组,差异均具有统计学意义(P<0.05),但两组新生儿窒息率和NRDS发生率差异无统计学意义(P>0.05);孕32～33+6周A组新生儿窒息率、NRDS发生率和早产儿病死率均高于B组,差异具有统计学意义(P<0.05)。③孕28～31+6周和孕32～33+6周B组宫内感染率均高于A组,差异均具有统计学意义(P<0.05),两组产褥感染率差异无统计学意义(P>0.05)。结论:针对不同孕周未足月胎膜早破患者的处理有不同策略,适当延长期待治疗时间可以改善妊娠结局。
Objective：To observe the effects of time option of expectant management on pregnancy outcomes in premature rupture of membranes（PROM） at 28-33（＋6） weeks of gestation.Methods：The clinical data were reviewed in 103 patients with PROM at their 28-33（＋6） weeks′ gestation.All patients were allocated to groups of 28-31（＋6） weeks（n=45） and 32-33（＋6） weeks（n=58）.By the time option for expectant management,the patients were further subgrouped into two regarding timing expectant management 〈 3 days（group A） or≥3 days（group B） for comparing the incidences of premature birth and complications in patients between groups.Results：①Compared with 32-33（＋6） weeks group,the incidence of neonatal asphyxia,neonatal respiratory distress syndrome（NRDS）,neonatal death and intrauterine infection risks was in general significantly higher in the group of 28-31（＋6） weeks（P〈0.05）;②In the group of 28-31（＋6） weeks,the incidence of neonatal deaths in group A was significantly higher than that in B group（P〈0.05）,whereas there were no statistical difference with neonatal asphyxia and NRDS（P〉0.05）.In the group of 32-33（＋6） weeks,the incidence of neonatal asphyxia,NRDS and neonatal death in group A was significantly higher than that in group B（P〈0.05）;③Significantly higher intrauterine infection risks was seen in group B at the 28-31（＋6）weeks and 32-33（＋6） weeks as compared with group A（P〈0.05）,but suggested no statistical difference regarding puerperal infection rate（P〉0.05）.Conclusion：Flexible management strategies can be applied to diverse weeks of gestation in patients with PPROM.Rational delay of the expectant management seems beneficial to a certain extent to the pregnancy outcomes.
出处
《皖南医学院学报》
CAS
2012年第4期298-300,共3页
Journal of Wannan Medical College
关键词
未足月胎膜早破
期待疗法
妊娠结局
preterm premature rupture of membranes （ PROM ）
ex-pectant management
pregnancy outcomes
