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未足月胎膜早破216例临床分析

Clinical analysis on 216 cases of preterm premature rupture of membranes
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摘要 目的回顾性分析笔者所在医院216例未足月胎膜早破患者的相关发病因素、分娩方式及对母儿的影响以指导临床。方法将216未足月胎膜早破患者按孕周分为三组,28周~31^+6组、孕32~34^+6周组及35周~36^+6周组。统计胎膜早破相关因素,对比不同孕周分娩方式、不同孕周围生期情况。结果胎膜早破的发生率为12.3%,而PPROM发生率为1.47%;PPROM相关因素的构成比中,生殖道感染最高24.5%,其次为胎位异常22.2%,流产、引产史19.0%;孕28~31^+6周组的剖宫产率低于孕32—~34^+6周组和孕35~36^+6周组(P〈0.05);而孕32~34^+6周组与孕35~36^+6周组比较,无统计学意义(P〉0.05)。孕28~31^+6周组新生儿窒息率、新生儿肺炎患病率及新生儿病死率均高于孕32~34^+6周及孕35~36^+6周组,差异有统计学意义(P〈0.05);而孕32~34^+6周组与孕35~36^+6周组比较,差异无统计学意义(P〉0.05)。结论生殖道感染;胎位异常、头盆不称;流产、引产史是引起本组PPROM的主要因素,临床上应针对相关因素尽量预防。PPROM围生儿结局与孕周密切相关。选择何种分娩方式对母婴有利.应结合临床实际综合考虑。 Objective To retrospective study on 216 cases of preterm premature rupture of the membrane(PPROM) in my hospital, including its relative factors,parturition patterns and influence to mother and child. Methods All 216 cases were divided into three groups, 28 -31^+6weeks group,32- 34^+6 weeks group and 35 -36^+6 weeks group. Some targets, such as relative factors of PPROM, parturition patterns,neonate conditions in different gestational weeks. Results The prevalence of PROM among all pregnant women was 12.3% , while PPROM was 1.47%. The correlative factors occurred in the 216 cases of PPROM as the following proportion:genital tract infection for 24. 5% ,abnormal fetal position 22.2% ,history of abortion and induced abortion 19.0%. The cesarean section rate in 28 -31^+6 gestational week group was lower than that in the 32 - 34^+6 or 35 - 36^+6 weeks group (P 〈 0.05 ), while 32 - 34^+6 weeks group presented no difference from that in the 35 - 36^+6 weeks group (P 〉 0.05 ). The complicated syndrome of neonate in the 28 - 31^+6gestational week group was higher than that in the 32 - 34v gestational week group or 35 - 36^+6 gestational week group ( P 〈 0.05 ), while 32 - 34^+6 weeks group presented no difference from that in the 35 - 36^+6 weeks group (P 〉 0.05 ). Conclusion Genital tract infection, abnormal fetal position, history of abortion and induced abortion may be the major related factors of PPROM. PPROM should be prevented according to the related factors. Newborn outcomes are associated to gestational weeks, we need consider method together with clinical practice to select what parturition patterns is benefit for mother and child.
出处 《中外医学研究》 2010年第30期11-13,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 未足月胎膜早破 回顾性研究 相关因素 剖宫产 围生儿结局 Preterm premature rupture of membranes Retrospective study Correlation factor Cesarean delivery Perinatal outcome
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