摘要
目的:为了考察蛋清肽-钙配合物(EWP-Ca)在动物体内的补钙效果。方法:将60只Wistar雄性大鼠随机分为6组:普通组、缺钙模型组、CaCO3组以及低、中、高剂量EWP-Ca组,通过构造缺钙大鼠模型,进行了为期30d的补钙实验,实验结束后对各种与补钙相关的指标进行测定。结果:与缺钙模型组相比,高剂量EWP-Ca组(Ca剂量为106.4mg/(kg.d))能极显著增加大鼠股骨直径、干质量、骨钙含量及股骨密度(P<0.01),极显著降低血清碱性磷酸酶(AKP)活力(P<0.01);与钙含量相同的CaCO3组相比,EWP-Ca高剂量组股骨直径、骨钙含量极显著和显著增加(P<0.01,P<0.05)。结论:EWP-Ca具有体内促进钙吸收作用,且效果优于钙含量相同的CaCO3。
Objective： To explore the promoting effect of egg white peptide binding with calcium（EWP-Ca） on calcium absorption in vivo.Methods： Totally 60 male Wistar rats were randomly divided into 6 groups： normal group,calcium-deficient model group,CaCO3 group and EWP-Ca groups at low,medium and high doses.Calcium-deficient model rats were fed a low-Ca diet,and calcium absorption-related indices were determined after a feeding period of 30 days.Results： EWP-Ca at high dose（106.4 mg/（kg·d）） could significantly increase femur diameter,dry weight,calcium content and bone mineral density（P〈0.01） and could significantly decrease the activity of serum alkaline phosphatase（AKP）（P〈 0.01） when compared with calcium-deficient model control group.Moreover,compared with CaCO3 group at the same calcium level,femur diameter（P〈0.01） and bone calcium content（P〈0.05） were significantly increased.Conclusion： EWP-Ca can promote calcium absorption in vivo,which is better than CaCO3 at the same calcium level.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2012年第11期262-265,共4页
Food Science
关键词
蛋清肽
蛋清肽-钙配合物
促钙吸收
补钙制剂
egg white peptide
egg white peptide binding with calcium （EWP-Ca）
calcium absorption-promoting effect
calcium supplement
