摘要
目的了解医院血培养分离出的病原菌的分布情况及耐药性,为合理用药提供依据。方法对2006-01至2011-01血培养结果进行回顾性分析。手工法培养血液标本,阳性者分离所得菌株采用国产半自动微生物仪进行生化和药敏试验。结果 2300份送检标本检出305株病原菌,阳性率13.3%。其中革兰阴性杆菌172株,占56.39%;革兰阳性球菌114株,占37.38%;真菌19株,占6.23%。革兰阴性杆菌对美洛培南、哌拉西林/他唑巴坦、左氧氟沙星、阿米卡星、磷霉素敏感性较高;万古霉素仍然是阳性球菌最敏感的抗生素。结论对血行感染的病原菌进行耐药性检测,对指导合理应用抗生素具有重要意义。
Objective To investigate the distribution and drug resistance of isolates from blood specimens in this hospital from 2006 to 2011 so as to contribute to clinical diagnosis and treatment.Methods Isolates were obtained from blood culture bottles.The isolates were identified and the results of antibiotic resistance were analyzed by the half-automated blood culture system.Results 305 strains were isolateded from 2300 blood specimens（13.3%）,including 172 Gram-negative（G-）bacteria（56.39%）,114 Gram-positive（G＋）bacteria（37.38%）,and 19 fungi（6.23%）.Gram-negative bacteria were more susceptible to meropenem,piperacillin / tazobactam,levofloxacin,amikacin,and fosfomycin than to the cephalosporin antibiotics.Gram-positive bacteria were most susceptible to vancomycin.Conclusions The species and drug resistance of the bacteria isolated from blood specimens have changed.More attention should be paid to the detection and surveillance of bacterial resistance in blood culture to promote the rational use of antibiotics.
出处
《武警医学》
CAS
2012年第4期290-292,295,共4页
Medical Journal of the Chinese People's Armed Police Force
关键词
血培养
病原菌
耐药性
抗生素
blood culture
isolates
antimicrobial agents
resistance
