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自拟明目汤结合西药对原发性闭角型青光眼视神经功能保护作用研究 被引量:6

A Study on the Protective Effects of Zinimingmu Tang on Glaucoma Optic Nerve
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摘要 目的探讨自拟明目汤结合西药对原发性闭角型青光眼视神经损害的保护作用。方法 30例患者(60只眼)随机分为中西药结合治疗组(实验组)14例(28只眼)和对照组16例(32只眼),对照组以脑蛋白水解物注射液静滴治疗,治疗组在对照组基础上加用自拟明目汤,4周后对两组患者行视力、视野、图形视觉诱发电位(P-VEP)检查。结果治疗4周后两组患者平均光敏度和db均存在明显差异(P<0.05),两组患者P-VEP振幅和潜伏期均存在明显差异(P<0.05);两组患者视力恢复总有效率差异明显(P<0.05)。结论明目汤结合西药治疗能有效缓解视神经功能的损害。 Objective To discuss the protective effects of Zinimingmu Tang on primary angle-closure glaucoma optic nerve.Methods 30 cases(60 eyes) of those patients were randomly divided into two groups: Chinese and Western medicine combination therapy group with14 patients(28 eyes) and control group with 16 patients(32 eyes).The control group was given intravenous protein hydrolysates,while the experimental group was given intravenous protein hydrolysates plus Zinimingmu Tang.After 4 weeks,observations on two groups of patients were made on eyesight,field of vision and P-VEP.Results Comparing results of two groups after 4 weeks of treatment,mean light sensitivity and db were significantly different(P0.05).The results of P-VEP and incubation period in two groups were significantly different(P0.05).The visual acuity in patients with total efficiency in control group was 53.13% and was 85.71% in experimental group,χ2=9.89,so the results were significantly different(P0.05).Conclusion Mingmu Tang combined with western medicine can alleviate effectively the damage of the optic nerve.
作者 夏向军 李进
出处 《湖北民族学院学报(医学版)》 2012年第1期43-45,共3页 Journal of Hubei Minzu University(Medical Edition)
关键词 明目汤 青光眼 视神经损害 保护 Mingmu Tang glaucoma optic nerve injury protection
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