摘要
目的:了解南京地区儿童细菌性腹泻中致病性大肠埃希菌(Escherichia coli,E.coli)的主要血清型和对抗生素的敏感性。方法:对5 409例粪便标本进行分离培养并用血清学方法鉴定E.coli血清型,采用纸片扩散法测定E.coli对常用抗生素的敏感性。结果:5 409例粪便标本中分离出633株E.coli,检出率为11.70%;血清学分型共检出12种血清型,产超广谱β-内酰胺酶菌株的检出率达82.15%。结论:E.coli是引起儿童细菌性腹泻的一种重要致病菌,且多重耐药情况严重;临床应开展对E.coli的检测并应根据药敏试验结果合理选用抗菌药物治疗E.coli感染。
Objective：To survey the serotype and antibiotics resistance of enteropathogenic Escherichia coli（E.coli） in children with diarrhea in Nanjing area.Methods：Five thousand four hundred and nine cases of feces samples were cultured,isolated E.coli strains were indentified by serotyping,and the antibiotic susceptibility was determined by disk diffusion test.Results：Six hundred and thirty-three strains of E.coli were isolated（11.70%） and 12 serotypes were detected.The incidence of ESBLs was 82.15% in the isolated strains.Conclusions：E.coli is an important pathogen leading to infant diarrhea,and highly resistant to many antibiotics;we should identify E.coli and select correct antibiotics according to the results of susceptibility test.
出处
《蚌埠医学院学报》
CAS
2011年第12期1380-1381,1384,共3页
Journal of Bengbu Medical College
