摘要
目的了解大肠埃希菌(ECO)及肺炎克雷伯菌(KPN)产超广谱β-内酰胺酶(ESBLs)菌株的分布情况及其药敏特点,指导临床用药。方法用K-B法及纸片确证试验,对582株ECO及KPN产ESBLs菌株进行检测和分析。结果582株菌中共检出128株产ESBLs菌株,总检出率为22%,产ESBLs株对大部分抗菌药物耐药,而对亚胺培南100%敏感。结论产ESBLs菌株是临床常见致病菌,亚胺培南是治疗产ESBLs菌株感染的首选药物。
OBJECTIVE To study the distribution and characteristic about drug resistance of extended-spectrum β- lactamases （ESBLs） producing Klebsiella pneumoniae and Escherichia coli for guiding the clinical drug using. METHODS Using K-B agar diffusion method and confirmed test to detect the drug resistance and distributions of ESBLs-producing K. pneumoniae and E. coil RESULTS Among 582 K. pneumoniae and E. coli isolates, 128（22%） were ESBLs-producing strains. For E. coli, the ratio was 17.5%, while K. pneumoniae was 28.3%/00. The sensitive rate of K. pneumoniae to imipenem was 100%. CONCLUSIONS ESBLs-producing K. pneumoniae and E. coli are the most common species causing infections, and imipenem is the best choice.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2007年第4期455-456,共2页
Chinese Journal of Nosocomiology
