摘要
目的 :观察天灸抗化疗骨髓抑制副作用的效应。方法 :天灸“大椎”、“肾俞”、“足三里”穴 ,检测环磷酰胺化疗大鼠外周血白细胞、骨髓有核细胞及骨髓显微结构。结果 :大鼠第 1、 4天腹腔注射环磷酰胺后 ,第 5～ 9天白细胞呈持续低值期 ,第 10天骨髓有核细胞和白细胞计数显著减少 ,骨髓象见造血细胞基本消失 ;而天灸可促进骨髓增生活跃 ,缩短化疗所致白细胞持续低值期 ,提前恢复白细胞数 ,尤以刺激量适中的天灸 组效果为佳。结论 :提示天灸可以改善化疗大鼠骨髓造血功能 ,且与天灸的刺激量有关。
Objective:To study the effect of medicinal vesiculation on bone marrow inhibition caused by chemotherapy.Methods:Peripheral WBC,bone marrow karyocyte and bone marrow ultrastructure of rats treated by CTX were explored after medicinal vesiculation on “Dazhui”,“Shenshu”and“Zusanli”.Results:The bone marrow karyocyte and WBC were significantly reduced after ten days treated by CTX,and hematopoiesis cells almost disappeared.Medicinal vesiculation could remarkably promote bone marrow cell prolieration,increase the number of karyocyte of bone marrow and WBC significantly,especially in group Ⅱ.Conclusions:Our studies indicated that medicinal vesiculation proved hematopoietic function of rats treated by chemotherapy,and the amount of stimuli could contribute to this effect.The results above were important to treat inhibition of bone marrow caused by chemotherapy.
出处
《浙江中医学院学报》
2000年第1期74-78,共5页
Journal of Zhejiang College of Traditional Chinese Medicine
关键词
天灸
针灸疗法
肿瘤
药物疗法
造血功能
medicinal vesiculation,cyclophosphamide/side effect,white blood cell,bone marrow karyocyte,bone marrow/microstructure
