摘要
为探讨口腔粘膜下纤维性变(OSF)中胶原增生的机制,透射电镜下对成纤维细胞分类计数,结果表明合成胶原功能最旺盛的成胶原细胞在病变早期、中期增多,降解胶原能力最强的破纤维细胞在病变中期、晚期减少,其差异均有显著性。提示OSF中胶原纤维的堆积在早期主要为合成的增多,中期既有合成的增多,也有降解的减少。
In order to understand the causes of accumulation of collagen in oral submucous fibrosis (OSF), two main types of fibroblast (Fb), the collagenoblasts and fibroclasts,were counted under transmission electron microscopy. The results showed that:the collagenoblasts increased at the early and moderately advanced stages of OSF; the fibroclasts decreased at the moderately advanced and advanced stages of OSF. The results suggested that the increase of collagen synthesis and the decrease of its degradation by Fb could result in collagen accumulation.
出处
《临床口腔医学杂志》
2000年第1期8-9,共2页
Journal of Clinical Stomatology
