摘要
[目的 ] 探讨抗生素在预防心脏瓣膜替换术后感染的合理应用。 [方法 ] 将 1996年～ 1999年 12 0例实施心脏瓣膜替换手术的病例分三组 ,分别给予不同抗生素的种类 ,观察不同应用时机和术后疗程的术后感染并进行比较。 [结果 ] 术后各种感染发生在青霉素类、头孢菌素类和喹诺酮类三组差异无显著性 ,给药时机 ,术晨 ,麻醉诱导前 ,切皮时无差异 ,疗程术后 5天和 7天无差异。 [结论 ] 预防性抗生素应用在心脏瓣膜替换手术中确有必要 ,抗生素使用以青霉素类为首选 ,手术切皮时给药一次为最佳时机 ,疗程术后 5天为宜。
Objective] This sutdy explored the reasonable application of antibiotic to prevent postoperative infection in cardiac valve replacement.[Methods] 120 cases of operated cardiac valve replacement from 1996 to 1999 were diveded into three groups. Each group was given different antibiotics and observed postoperative infection during different applied period and postoperative treatiment courses. The postopenative infection rate after different antibiotics application was compared by chi-aqured (χ 2) test.[Results] Postoperative infection rates were no difference with the application of penicillins, quinoloes and cephalosporings whether applied period or postoperative treatment courses.[Conclusion] Preventive antibiotic application was necessary in cardiac valve replacement. Penicilling were the best choice for cardiac valve replacement, most important applied period was during operating skin and postoperative treatmen courses was enough in 5 days.
出处
《实用预防医学》
CAS
2000年第1期22-23,共2页
Practical Preventive Medicine
关键词
抗生素
心脏瓣膜替换术
感染
预防
Antibiotics,Postoperative infection, Cardiac valve replacment.
