摘要
目的：研究呋喃西林溶液的化学稳定性。方法：用紫外分光光度法于波长３７４ｎｍ 处测定呋喃西林溶液的含量，分别通过经典恒温法和初均速法对呋喃西林溶液作稳定性实验，并与留样观察作对照。结果：２ 种方法测得呋喃西林溶液的室温贮存期￡２５℃０．９ 分别为８７ｄ 和８４ｄ ，与留样观察结果也基本相符。结论：初均速法测定药物的稳定性是一个简便易行的方法。
OBJECTIVE:Tu study the chemical stability of Furacillin solution.METHOD:The concentration of Furacillin solution were determined with UV spectrophotometry at 374nm.Classical constant temperature and initial average rate method were applied to test the stability of Furacillin solution which was compared with samples reserved for observing.RESULTS:The shelflife of furacillin solution at room temperature ￡ 25℃ 0.9 determined by two methods was 87days and 84days respectively.CONCLUSION:Initial average rate method is a simple way to determine the stability of drug.
出处
《中国现代应用药学》
CAS
CSCD
1999年第6期53-55,共3页
Chinese Journal of Modern Applied Pharmacy
关键词
呋喃西林
溶液
化学稳定性
classic isothermal tests,initial average rate method,furacillin,stability
