摘要
目的研究中药胆木叶的水溶性成分。方法应用多种色谱方法进行分离纯化,通过1H-NMR、13C-NMR等波谱技术确定化合物的结构。结果从胆木叶乙醇提取物的水溶性成分中分离得到5个化合物,其中4个配糖体。经过波谱和理化性质分析分别鉴定为3,4-二羟基苯甲酸(I)、胡萝卜苷(II)、山萘酚-3-O-(6″-O-α-L-鼠李吡喃糖基)-β-D-葡萄吡喃糖苷(Ⅲ)、芦丁(Ⅳ)和Pumiloside(V)。结论化合物I、Ⅲ和Ⅳ首次从该植物中分离得到。
Objective To investigate the water-soluble fraction of the ethanol extract from the leaf of Nauclea officinalis.Methods The chemical constituents were isolated by various chromatography techniques,and structurally elucidated by spectral evidence together with physiochemical analysis.Results Four compounds were isolated from the Water-Soluble fraction of the ethanol extract from the leaf of N.officinalis,and their structures were identified as 3,4-dihydroxybenzoic aci（Ⅰ）,daucosterol（Ⅱ）,kaempferol-3-o-β-D-（6″-O-α-L-rhamnepy ranosyl） glucopyranoside（Ⅲ）,rutin（Ⅳ） and Pumiloside（V）.Conclusion Compounds Ⅰ,Ⅲ and Ⅳ were isolated from N.officinalis for the first time.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2011年第5期1110-1111,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家科技支撑计划(No.2007BAI27B04)
关键词
胆木
水溶性成分
配糖体
Nauclea officinalis
Water-soluble constituent
Glycoside
