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胃癌KAI1/CD82、ME491/CD63的表达及与临床病理特征的关系 被引量：2

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摘要 目的探讨胃癌组织中KAI1/CD82、ME491/CD63的表达及与临床病理的关系。方法应用免疫组化SABC法,检测63例胃癌组织中KAI1/CD82、ME491/CD63的表达,比较其与临床病理的关系。结果无淋巴结转移,病理分化Ⅰ、Ⅱ级,癌组织面积小的胃癌组织KAI1/CD82阳性表达率高于有淋巴结转移、病理分化Ⅲ级、癌组织面积大者,差异有统计学意义(P<0.05);ME491/CD63表达与有无淋巴结转移、病理分级程度、浸润深度、癌组织面积大小,差异无统计学意义。结论 KAI1/CD82可作为胃癌的预后指标。
作者 赵玉芳 季润元 束晓明 王娟 林波 冯振卿
机构地区 淮安市楚州医院病理科 江苏省淮阴卫生高等职业技术学校淮安市消化道肿瘤重点实验室 淮安市第一人民医院妇产科 南京医科大学病理学系
出处 《江苏医药》 CAS CSCD 北大核心 2011年第18期2192-2193,共2页 Jiangsu Medical Journal
基金 江苏省淮安市科技局项目(HASZ09019)
关键词 KAI1/CD82 ME491/CD63 胃癌 相关性
分类号 R735 [医药卫生—肿瘤]
  • 相关文献

参考文献11

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二级参考文献31

共引文献14

同被引文献11

  • 1Dong JT,Lamb PW,Rinker Schaeffer CW,etal.KAI1, a metastasis supperssor gene for prostate cancer on human chromosome 11p11.2[].Science.1995
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  • 3Guo XZ,Friess H,Maurer C,et al.KAI1 is unchanged in metastatic and nonmetastatic esophageal and gastric cancer[].Cancer Research.1998
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  • 7Jackson P,Rowe A,Gri mm M O.An alternatively spliced KAI1mRNAis expressed at lowlevelsin human bladder canc-ers and bladder cancer cell lines andis not associated withinva-sive behaviour[].Oncology Reports.2007
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  • 9Jian-Hua Xu Xiao-Zhong Guo Li-Nan Ren Li-Chun Shao Min-Pei Liu.KAI1 is a potential target for anti-metastasis in pancreatic cancer cells[J].World Journal of Gastroenterology,2008,14(7):1126-1132. 被引量：15
  • 10季润元,束晓明,张徐宁,李雪甫,沈阳,王成海,冯振卿.食管癌组织KAI1/CD82、MRP1/CD9的表达及其临床意义[J].江苏医药,2010,36(13):1498-1501. 被引量：8

引证文献2

二级引证文献4

江苏医药
2011年 第18期

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