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静脉推注心律平与西地兰对快速性心房颤动的疗效比较 被引量:1

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摘要 目的分别用心律平与西地兰静脉推注治疗快速性心房颤动,观察其复律成功率及作用时间,并对其进行疗效比较。方法将47例快速性心房颤动患者按所给药物分为两组。心律平组:心律平70mg(规格:35mg/10ml)于5min内静脉注射,30min房颤未终止者再重复应用70mg,持续静脉点滴至房颤终止或心室率降至100次/min以下;西地兰组:西地兰0.4mg(〉70岁患者首次量用0.3mg)5~10min内静脉推注,30min房颤未终止者再重复应用0.2mg,最大量不超过0.8mg/天(〉70岁患者减量)。记录用药至房颤终止或心室率降至100次/min以下的时间,观察其复律成功率,以及血压、心率、心电图及不良反应的情况。结果心律平组30min内,30min,60min,120min,180min,480min复律成功率(25.00%,41.67%,58.33%,62.50%,70.83%,79.17%)明显高于西地兰组复律成功率(4.35%,13.04%,26.09%,30.43%,39.13%,47.83%),复律时间[(30.7±9.5)min]短于西地兰组[(40.8±12.4)min](P均〈0.05),且不良反应少。结论用心律平注射液治疗快速性心房颤动比用西地兰静脉推注更有效,时间更短,更安全。
出处 《右江民族医学院学报》 2010年第6期856-857,共2页 Journal of Youjiang Medical University for Nationalities
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