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西地兰治疗外加用硫酸镁治疗房颤伴快速心室率患者的作用和安全性 被引量:3

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摘要 目的探讨房颤伴快速心室率采用西地兰外加用硫酸镁治疗的临床效果及安全性。方法选择我院2009年5月至2011年5月收治的房颤伴快速心室率患者80例,随机分为两组,对照组40例采用西地兰治疗,观察组40例在此基础上加用硫酸镁治疗,就两组临床资料进行回顾性分析。结果两组平均收缩压用药前无明显差异,用药后均有所下降,但差异无统计学意义(P>0.05)。观察组心室率在用药前比较无明显差异。用药后观察组降至100次/min例数明显多于对照组,差异有统计学意义(P<0.05)。两组用药后转复为窦性心律的例数观察组显著多于对照组(P<0.05)。见表1。两组不良反应均以头晕、心动过缓、低血压、面色潮红为主,观察组3例,对照组2例,均自行缓解,无统计学差异(P>0.05)。结论房颤伴快速心室率患者采用西地兰外加用硫酸镁治疗,可显著控制心室率和提高窦性心律转复率,具有一定的安全性和有效性,显著改善了患者生存质量。
作者 王秋敏
出处 《中国医药指南》 2012年第27期232-233,共2页 Guide of China Medicine
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