摘要
目的：探讨肥胖对糖尿病发生及其并发症的影响。方法：对北京地区，年龄≥25岁的1657人群进行标准口服葡萄糖耐量试验及糖尿病并发症检查。结果：体重指数（BMI）≥25的肥胖者，糖尿病、糖耐量减低的患病率均显著高于BMI＜25者（P＜0．01）。BMI≥25的糖尿病患者高血压、脑卒中患病率亦高于BMI＜25的糖尿病患者，而视网膜病变的患病率低于后者。糖尿病肾病的患病率在肥胖与非肥胖两组相同。结论：肥胖是糖尿病、糖耐量减低及其高血压、脑卒中的重要危险因素，而在微血管并发症的作用有待于进一步探讨。
To investigate the effect of obesity on diabetes and its complications. A randomly selected 1 657people aged ≥25y, were screened for diabetes and impaired glucose tolerance (IGT) using standard 75g oral glucose tolerance test (OGTT). The relationship between obesity and prevalence of diabetes and its complications were investigated. Results showed that the incidence of DM and IGT was higher in people with body mass index (BMI)≥ 25 than those with BMI < 25. Of the DM subjects, the incidence of hypertension and stroke were higher in those with BMI≥ 25 than those with BMI<25,while the incidence of retinopathy was lower in those with BMI≥ 25. The incidence of diabetic nephropathy was almost the same in these two groups. This indicates obesity is a risk factor for DM and its macrovascular complications, but the effect of obesity on the DM microvascular complication remain to be further investigated.
出处
《基础医学与临床》
CSCD
1999年第3期47-52,共6页
Basic and Clinical Medicine
关键词
肥胖
糖尿病
糖耐量减低
并发症
Obesity Diabetes Mellitus Impaired Glucose Tolerance Complication
