摘要
对１０例尸检心脏标本进行了肌动蛋白（Ａｃｔｉｎ，Ａｔ）的免疫组化观察。依据Ｄａｌｓ标准的明确或界限性病毒性心肌炎５例，心肌组织内Ａｔ含量减损，呈局灶性或弥漫性淡染，偶见小灶性单个心肌细胞内Ａｔ缺失。心肌梗死２例，心肌组织内Ａｔ大片缺失；非心性死亡对照组３例，心肌组织内Ａｔ呈均匀一致的强阳性染色。结果表明，心肌组织内Ａｔ的免疫组化观察可望提高对不典型病毒性心肌炎诊断的敏感性。
10 specimens of heart in autopsy were
immunohistochemically studied by using anti-actin(At) antibody. In 5 cases with definite or
suspected viral myocarditis according to Dallas criteria, actin in myocardium showed focal or
diffuse weak staining, and occasionally showed focal absence of staining. In 2 cases with
myocardial infarction, actin showed large pieces absent of staining, while actin in 3 cases with
non-cardiac death showed strongly positive, well-distributed staining. The results indicated the
immunohistochemical observation of actin in myocardium is useful for improving the sensitivity
in diagnosing viral myocarditis and differentiating the slight injuries of myocytes caused by
ischemia or inflammation.
出处
《法医学杂志》
CAS
CSCD
1999年第2期75-76,共2页
Journal of Forensic Medicine
