摘要
目的评价枸杞粉(滋补肝肾中药)对老年人体质状态的影响。方法用双盲、随机、安慰剂对照的临床试验设计,按年龄和性别进行分层。对健康老年人群(65～70岁,男女均衡)补充3个月枸杞粉前后中医证候的观察,给药组和对照组分别给予枸杞粉(每天13.7g)与安慰剂,每组75人。用中医诊断问卷,对补充枸杞3个月前后所有受试者的典型中医证候进行调查。结果和对照组相比,服用枸杞粉的老年人群的阴虚症状有明显改善,其中口干咽燥、心烦失眠和脉象3项指标均有显著性改善(P<0.01)。结论长期口服枸杞粉可使老龄人群的体质状况得到显著改善,这可能与枸杞中的抗氧化物质(玉米黄素)有关。
Objective To evaluate the effect of Wolfberry extract pow- der on the physical status in healthy elderly persons. Methods A ran- domized, double -blind, and placebo- controlled clinical study was conducted for treatment elderly persons, stratified by age and gender （65 -70 years, gender balanced） through observation of the subjects＂ syndromes of traditional Chinese medicine （TCM）. The treatment group and placebo group was treated with Wolfberry extract powder （ 13.7 g · d-1 ） and placebo of 3 months supplementation, respectively, 75 subjects for each group. TCM diagnosis questionnaires were used to collect information about the classical syndromes of TCM of all volunteers by two TCM doctors at the beginning and after 3 months of Wolfberry supplementation. Results Compared with the control group, the syndrome of Yin deficiency did significantly improve for subjects that received the Wolfberry extract powder, with dry mouth and throat, vexation and insomnia and pulse condition being significantly improved （ P 〈 0.01 ） over the placebo group. This change was paralleled with a significant increase of anti- oxidant capacity in the group supplemented with Wolfl^erry extract powder. Conclusion The results indicate that oral administration of Wolfberry extract powder can significantly improve the physical status of elderly persons during longterm supplementation, and that this is partially due to the richness of anti- oxidants （zeaxanthin） in Wolfberry.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2010年第10期729-732,共4页
The Chinese Journal of Clinical Pharmacology
关键词
枸杞
阴虚
口干咽燥
心烦失眠
Wolfberry
Yin deficiency
dry mouth and throat
vexation and insomnia
