摘要
目的:了解我院药品不良反应(ADR)发生的特点及一般规律。方法:收集我院2008～2009年上报的235例ADR报告,分别对患者的性别、年龄、给药途径、药品种类、ADR累及器官或系统及临床表现等进行统计、分析。结果:235例ADR报告中,60～79岁的患者ADR发生率最高,占27.66%;静脉给药途径ADR发生率最高,占90.21%;抗微生物药致ADR发生率最高,占52.77%;最常见的ADR临床表现为皮肤及其附件损害,占44.54%。结论:临床应重视ADR的报告和监测工作,合理应用抗微生物药和静脉注射药,以减少ADR的发生,促进临床合理用药。
OBJECTIVE：To investigate the regularity and characteristics of adverse drug reaction（ADR） occurred in our hospital.METHODS：A total of 235 ADR cases collected from 2008 to 2009 in our hospital were analyzed statistically in respect of patients＇ age and sex,routes of administration,kinds of drugs,organs and systems involved in ADR and clinical manifestations,etc.RESULTS：Of 235 ADR cases,27.66% were occurred in age group 60 to 79;90.21% were induced by intravenous administration;52.77% were caused by antibiotics;main clinical manifestation were lesion of skin and its appendants,accounting for 44.54%.CONCLUSION：Importance should be attached to reporting and monitoring of ADR.Antibiotics and intravenous drugs should be used rationally to reduce the incidence of ADR and promote rational use of drugs in the clinic.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第30期2863-2865,共3页
China Pharmacy
关键词
药品不良反应
报告
分析
合理用药
Adverse drug reaction
Report
Analysis
Rational use of drugs
