摘要
目的:监测我院2006～2008年肠球菌中粪肠球菌株和屎肠球菌株的耐药性,为临床合理应用抗菌药物提供依据。方法:采用K-B纸片法对分离鉴定后的肠球菌进行药敏试验,应用WHONET5软件统计粪肠球菌和屎肠球菌的耐药率。结果:万古霉素是敏感性最高的抗菌药物。粪肠球菌对青霉素、高浓度庆大霉素、环丙沙星、利福平的耐药率较低,而屎肠球菌对高浓度链霉素、四环素、氯霉素和奎奴普丁/达福普汀的耐药率较低。结论:粪肠球菌和屎肠球菌均呈多重耐药,临床用药应结合药敏试验结果,合理选择抗菌药物。
OBJECTIVE：To monitor the antimicrobial resistance of Enterococcus faecalis and Enterococcus faecium in our hospital from 2006 to 2008 in order to provide reference for clinical rational use of antibiotics.METHODS：The susceptibility of isolated enterococci was determined by K-B paper diffusion method,and the antibiotic resistance rates of Enterococcus faecalis and Enterococcus Faecium were analyzed using Whonet 5 software.RESULTS：Vancomycin was the most sensitive antimicrobial against Enterococcus faecalis and Enterococcus faecium.E.faecalis had low resistance rates to penicillin G,high concentration gentamicin,ciprofloxacin and rifampicin,while E.faecium had low resistance rates to high concentration streptomycin,tertracycline,chloromycetin,and qinupristin/dalforpristin.CONCLUSION：E.faecalis and E.faecium are multi-drug resistant.Antimicrobials should be used rationally based on the susceptibility test of E.faecalis and E.faecium.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第30期2836-2837,共2页
China Pharmacy
关键词
粪肠球菌
屎肠球菌
耐药性
抗菌药物
Enterococcus faecalis
Enterococcus faecium
Antimicrobial resistance
Antibiotics
