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全麻下CT引导下经皮穿刺射频消融治疗肝内特殊部位的恶性肿瘤 被引量:33

CT-guided percutaneous radiofrequency ablation of hepatic malignancies located in unusual regions under general anesthesia
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摘要 目的评价在CT引导下进行经皮穿刺射频消融(RFA)治疗肝内一些特殊部位的恶性肿瘤的可行性及临床价值。方法 18例肝脏恶性肿瘤患者,共有26枚肿瘤,分别位于膈下、肝门部、肝包膜下、下腔静脉旁、胆囊旁以及结肠旁等肝内的特殊部位。所有患者均先行TACE治疗,然后在全麻和CT引导下行经皮穿刺RFA治疗,观察穿刺、布针所费的时间。随访1~15个月,观察并发症和疗效。结果所有患者费时为1~3min完成穿刺、布针。26枚肿瘤共进行了35次RFA治疗,未出现任何严重并发症。20枚肿瘤完全坏死;6枚部分坏死。结论本研究的结果表明,在全麻和CT引导下对肝内特殊部位恶性肿瘤进行经皮穿刺RFA治疗是可行的,在降低RFA的操作难度和风险方面具有一定的临床价值。 Objective To discuss the feasibility of CT-guided percutaneous radiofrequency ablation (RFA) of liver malignancies located in unusual regions under general anesthesia,and to assess its clinical value.Methods Eighteen patients with a total of 26 malignant hepatic lesions were enrolled in this study.The lesions were located at diaphragmatic surface,hepatic hilum,hepatic subcapsular site,side of inferior vena cava,side of gallbladder or near by colon.Transcatheter arterial chemoembolization was performed in all patients,which was followed by CT-guided percutaneous RFA under general anesthesia.The time used for puncturing and the time used for putting the needles to the scheduled sites were recorded.A follow-up for 115 months was conducted.The complications and the therapeutic results were observed.Results For all patients,the procedure of puncture and needle placement was completed in 1-3 minutes.A total of 35 RFA procedures were conducted for 26 lesions.No severe complications occurred.Complete necrosis was observed in 20 tumors and partial necrosis in 6 tumors.Conclusion The result of this study indicates that CT-guided percutaneous RFA under general anesthesia is a feasible technique for the treatment of liver malignancies located at unusual regions.This technique is very helpful for reducing the manipulating difficulty and lowing the complication risk of RFA procedures.
出处 《介入放射学杂志》 CSCD 北大核心 2010年第6期478-481,共4页 Journal of Interventional Radiology
关键词 肝肿瘤 射频消融 全身麻醉 CT引导 hepatic tumor radiofrequency ablation general anesthesia CT-guidance
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参考文献15

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