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射频消融及组合方案治疗特殊/高危部位肝癌的中远期疗效 被引量:14

The mid-to-long term efficacy of radiofrequency ablation together with combination regimen for the treatment of hepatic carcinomas located at special or high-risk regions
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摘要 射频消融(RFA)是目前肝癌患者非手术疗法的疗效较肯定的疗法之一,由于特殊/高危部位肝癌位置的特殊性导致操作难度系数增大,术后并发症发生率和肿瘤复发率更高,而完全坏死率和中远期生存率却更低。RFA联合多种组合方案,如经肝动脉化疗栓塞(TACE)、经皮注射无水乙醇(PEI)和靶向化疗等能更有效的提高肿瘤完全坏死率和患者的中远期生存率。本文就此作一综述。 Radiofrequency ablation (RFA) has now been one of the reliable and effective local therapies that are employed for patients with inoperable hepatic carcinoma or for patients who are unwilling to accept the surgical resection. Because of the particular locations of some hepatocellular carcinomas that are situated at the special or high- risk regions, the operation for these lesions are extremely difficult and the incidence of postoperative complications as well as the recurrence rate is unavoidably higher, meanwhile the complete necrosis rate of the tumors and the mid-to-long term survival rate of the patients are usually lower. RFA combined with a variety of combination therapies, such as transcatheter arterial ehemoembolization (TACE), percutaneous ethanol injection (PEI), targeted chemotherapy, etc. can improve the complete necrosis rate of such tumors as well as increase the mid-to-long term survival rate. This paper aims to make a general review in this respect.(J Intervent Radial, 2013, 22: 525-528)
出处 《介入放射学杂志》 CSCD 北大核心 2013年第6期525-528,共4页 Journal of Interventional Radiology
关键词 肝癌 射频消融 组合方案 特殊 高危部位 hepatic carcinoma radiofrequency ablation combination regimen special or high- risklocation
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