摘要
目的探讨特殊部位肝恶性肿瘤超声引导下经皮射频消融治疗的安全性、有效性及布针技巧。方法回顾分析2001年11月至2004年8月行超声引导下经皮冷循环射频治疗肝恶性肿瘤患者112例的资料,比较其中46例52个位于胆囊旁、包膜下、肝门部大血管旁等较特殊位置及66例86个非上述特殊部位肿瘤消融治疗的副作用及疗效。结果46例特殊部位肝肿瘤射频消融治疗均顺利进行,未发生严重的并发症,但局部肝周积液(17.4%)和胆囊壁水肿(19.6%)发生率高于非特殊部位组(P=0.0246,P=0.0009);术后1个月复查甲胎蛋白,甲胎蛋白的变化两组比较差异无显著性意义(P>0.05);术后3个月CT复查完全消融41个,局部残留10个,部分消融1个,与非特殊部位组比较差异无显著性意义(P>0.05)。结论靠近胆囊、肝包膜及肝门部等特殊部位的肿瘤并不是行冷循环射频治疗的禁忌证,只要进针点和路径选择合理,它仍然是一种有效的治疗方法。
Objective To investigate the safety, effectivity and needle technique of ultrasound-guided percutaneous radiofrequency ablation （PRFA） for treatment of particular-location liver malignancies. Methods One hundred and twelve patients with liver malignancies treated by PRFA from November 2001 to August 2004 were analyzed retrospectively. Side effect and efficacy were compared between 52 lesions of 46 cases located especial position such as gallbladder side ,next to integument, large vessels in portal fissure and 86 lesions of 66 cases not located above-mentioned especial position. Results Forty-six patients with especial position hepatic malignancy underwent ultrasound-guided PRFA successfully, there were no major complications occurring in all procedures, but the occurrences of peripheral liver effusion（17.4%）, and cystic paries edema（19.6%） were significantly higher than that in no especial position cases（ P = 0. 0246 and P = 0. 0009）. The change of AFP after one month was not significantly different between two groups （P〉0. 05）. CT examination showed complete ablation in 41 lesions, local residual lesions 10,and local ablation 1 after 3 months in especial position group, there were no significant differentce than that in no especial position group（ P〉0.05）. Conclusions Liver tumor located in special part was not the contraindication of PRFA. If the puncture point and route is selected properly, PRFA is an optional effective method to particular-location liver malignancy.
出处
《中华超声影像学杂志》
CSCD
2005年第9期659-663,共5页
Chinese Journal of Ultrasonography
