摘要
目的:观察地黄饮子对β淀粉样蛋白(Aβ25-35)诱导的PC12细胞损伤的保护作用。方法:通过HE染色、尼氏染色、电镜观察地黄饮子对细胞形态的影响。结果:地黄饮子可显著改善Aβ25-35损伤引起的PC12细胞形态的改变,减轻细胞膜的损伤,减少损伤所致的细胞死亡。结论:地黄饮子对Aβ25-35所致PC12细胞损伤具有较好的保护作用。
Objective:To investigate the effect of decoction of Rehmanniae on the injury of PC12 cell induced by Aβ(β-amyloid protein). Methods: To investigate the change of conformation by HE Staining,Nissl's Staining and Electron microscope. Results: Decoction of Rehmanniae can prominently improve the conformation change of injurious PC12 cell, improve the cell energy,and reduce the injurious cellto death. Conclusion: Decoction of Rehmanniae canprotect the injurious cell.
出处
《中医药学报》
CAS
2010年第2期19-21,共3页
Acta Chinese Medicine and Pharmacology
基金
国家自然科学基金(30472128)
高等学校博士学科点专项科研基金资助项目(20050228005)