摘要
目的：探讨新城疫病毒疫苗对自然人群EB病毒VCA－IgA抗体转阴的作用。方法：使用新城疫病毒疫苗鼻腔喷雾法治疗血清EBV－VCA－IgA抗体1:10以上的自然人群31例，并与47例安慰剂治疗作对照。结果：治疗组的抗体滴度下降、转阴率（77．42％）和波动率（6．45％）明显高于对照组的自然下降、转阴率（40．42％）和波动率（2．13％）；而治疗组的抗体滴度不变率（12．9％）和上升率（3．23％）则明显低于对照组（分别为46．8％和10．6％）（P＜0．005）。结论；新城疫病毒疫苗治疗VCA－IgA抗体阳性自然人群，有促进抗体滴度下降或者转阴的潜在作用。
Objective: To investigate the negative-transforming effect of Newcastle disease virus vaccines on IgA antibody in persons with EB virus VCA. Methods: 31 persons with VCA-IgA positive from natural crowd were treated with NDV vaccines and compared with 47 persons treated with placebo. Results: The effective rate of falling plus negative-transforming rate of ie group receiving the therapy was 77. 42%; the undulating rate,6. 45 %; the unchanged rate, 12. 9 %; and the rising rate, 3. 23 %. Whereas, the rates mentioned above in the control group were 40. 42%, 2. 13%, 46. 8% and 10. 6% respectively. There was remarkable difference between the two groups (P <0. 005). Conclusion: NDV vaccines may have a potential effect of promoting the foiling and negative-transforming of EBV-VCA-IgA antibody titer
出处
《广西医科大学学报》
CAS
1998年第4期4-6,共3页
Journal of Guangxi Medical University
