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鼻咽癌高癌家系成员EB病毒VCA-IgA抗体水平分析

Analysis of Epstein-barr virus VCA-IgA level among members ofmultiple case nasopharyngeal carcinoma families
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摘要 目的 :探讨鼻咽癌高癌家系成员的EB病毒VCA IgA抗体水平。方法 :用免疫酶法分别检测高癌家系成员共416人和自然人群874人的VCA IgA抗体。结果 :高癌家系成员的VCA IgA阳性率为26.44%(110/416) ,明显高于自然人群的4.23 %(37/874)。结论 :鼻咽癌高癌家系成员中的高EB病毒感染率与鼻咽癌的高发病率相关。 Objective:To observe the Epstein-Barr virus(EBV)VCA_IgA level among members of multiple case nasopharyngeal carcinoma(NPC) families.Methods:The immune enzyme assay was used for detecting serum VCA_IgA in 416 persons from members of multiple case NPC families and 874 persons from common population.Results:The positive rate of EBV-VCA-IgA is 26.44% in the members of multiple case NPC families,which was significantly higher than that(4.23%) in the common population(p<0.001).Conclusion:The higher level of EBV infection was related with higher morbidity of NPC in the members of multiple case NPC families.
出处 《四川肿瘤防治》 2000年第3期140-141,共2页 Sichuan Journal of Cancer Control
关键词 鼻咽癌 EB病毒 VCA-IGA抗体 Multiple case NPC family EBV VCA_IgA
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