摘要
目的:研究防感煎剂对甲1型流感病毒感染小鼠体重以及免疫器官与肺脏的影响。方法:建立H1N1型流感病毒感染小鼠模型,动态观测防感煎剂对感染小鼠体重、胸腺、脾与肺脏指数及病理改变情况。结果:防感煎剂可以减轻感染后体重下降程度,有利体重恢复,并且减轻肺部炎症病变,抑制肺炎损害,减轻病毒对机体免疫器官的损害,中高剂量组作用明显。结论:防感煎剂能够减轻感染的严重程度,有利于疾病的控制和恢复。
Objective:To study the Fanggan decoction's influence on weight,immune organ and lung tissue of influenza virus A infected mice.Methods:After setting up the model of mouse infect of Influenza a virus(H1N1),we observed and detected the dynamic changes of mice weight,thymus index,spleen index,lung index and the degree of lung tissue injury.Results:Fanggan decoction can relieve the degree of weight loss,lung tissue injury and the immune organ damage,while,the middle and high dose of Fanggan decoction have better effects.Conclusion:Fanggan decoction can relieve the degree of viral infection and be beneficial to control and recovery.
出处
《中华中医药学刊》
CAS
2010年第2期239-242,共4页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省自然科学基金资助项目(Y206862)