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防感煎剂对流感病毒感染小鼠体重以及免疫器官与肺脏的影响 被引量:7

Fanggan Decoction's Influence on Weight Immune Organ and Lung Tissue of Influenza Uirus Infected Mice
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摘要 目的:研究防感煎剂对甲1型流感病毒感染小鼠体重以及免疫器官与肺脏的影响。方法:建立H1N1型流感病毒感染小鼠模型,动态观测防感煎剂对感染小鼠体重、胸腺、脾与肺脏指数及病理改变情况。结果:防感煎剂可以减轻感染后体重下降程度,有利体重恢复,并且减轻肺部炎症病变,抑制肺炎损害,减轻病毒对机体免疫器官的损害,中高剂量组作用明显。结论:防感煎剂能够减轻感染的严重程度,有利于疾病的控制和恢复。 Objective:To study the Fanggan decoction's influence on weight,immune organ and lung tissue of influenza virus A infected mice.Methods:After setting up the model of mouse infect of Influenza a virus(H1N1),we observed and detected the dynamic changes of mice weight,thymus index,spleen index,lung index and the degree of lung tissue injury.Results:Fanggan decoction can relieve the degree of weight loss,lung tissue injury and the immune organ damage,while,the middle and high dose of Fanggan decoction have better effects.Conclusion:Fanggan decoction can relieve the degree of viral infection and be beneficial to control and recovery.
机构地区 浙江省中医院
出处 《中华中医药学刊》 CAS 2010年第2期239-242,共4页 Chinese Archives of Traditional Chinese Medicine
基金 浙江省自然科学基金资助项目(Y206862)
关键词 H1N1型流感病毒 防感煎剂 抗病毒 肺脏病理 免疫器官 体重 H1N1 influenza virus Fanggan decoction antivirus lung pathology immune organ weight
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