摘要
对15例慢传输型便秘(STC)患者乙状结肠壁内一氧化氮合酶(NOS)的分布进行免疫组织化学研究和半定量分析,结果表明肌间神经丛NOS阳性细胞明显增多(P<0.05),粘膜下丛无明显变化(P>0.05).提示一氧化氮的过量产生抑制了肠平滑肌的收缩,可能是STC发病的原因之一.
By using semiquantitative immunohistochemistry, the distribution of nitric oxide syn-thase (NOS) in the sigmoid colons of 15 patients with slow transit costipation (STC) were investigated. The density of NOS positive neurons was higher in the myenteric plexus (P <0. 05), while at the submucous plexus there was no difference between the STC group and thecontrol group (P >0. 05). This suggest that an excessive production of NOS may cause persis-tent inhibition of contractions which could be one of the reasons of slow transit colon.
出处
《大肠肛门病外科杂志》
1998年第2期12-13,共2页
Journal of Coloproctological Surgery
