摘要
目的:探讨重组人乳铁蛋白(hLF)对体外培养的鼻咽癌细胞生长特性的影响。方法:MTT法评价hLF对人鼻咽癌细胞CNE、人肝脏细胞L02的生长抑制作用。结果:乳铁蛋白对人鼻咽癌细胞系CNE的增殖有抑制作用并呈现剂量依赖性,对正常细胞无抑制作用。结论:人乳铁蛋白可以抑制鼻咽癌细胞CNE的增殖。
Objective :To explore the effect of lactoferrin on proliferation of the cultured CNE cells in vitro. Methods : MTT assay was used to evaluate the growth inhibition effect of lactoferrin on CNE, L02 and CHO cell lines. Resuits :Laetoferrin significantly inhibited the proliferation of CNE cells in a dose -dependent manner, but had no effect on the normal cells. Conclusion:Laetoferrin could significantly inhibit the growth of CNE cells.
出处
《现代肿瘤医学》
CAS
2010年第1期15-17,共3页
Journal of Modern Oncology
关键词
人乳铁蛋白
细胞增殖
鼻咽癌
human lactoferrin
cell proliferation
nasopharyngeal carcinoma