摘要
胰岛素抵抗和瘦素抵抗是多种代谢性疾病共同的病理基础,是引起机体能量代谢紊乱的重要因素.多项研究发现两者存在交互影响,但对胰岛素抵抗和瘦素抵抗的探索多是独立进行.本文拟从两者在多个水平,多个环节的相互作用作一综述.
Leptin resistance and insulin resistance are the common pathology of various metabolic diseases, and make great contribution to the metabolic syndrome. Many researches have proved that the two processes affected each other, whereas the exploration of the resistance mechanism was often independently carried out. Here, we＇d like to make a review focusing on the relationship between leptin resistance and insulin resistance, and their interactions at multiple levels.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第15期1534-1539,共6页
World Chinese Journal of Digestology
基金
上海市教委重点学科基金资助项目
No.J50305~~
关键词
瘦素抵抗
胰岛素抵抗
信号
分子
Leptin resistance
Insulin resistance
Signaling
Molecule
