期刊文献+

支原体感染及耐药性变化分析 被引量:4

Infection and drug resistance analysis in mycoplasma
原文传递
导出
摘要 目的:对比分析2005年与2008年广州地区泌尿生殖系感染者支原体感染和药敏情况。方法:对2005年及2008年的泌尿生殖系感染者进行支原体培养并对阳性患者做10种药物的体外敏感试验。结果:2005年与2008年男性患者感染率是31%和30%,女性是38.7%和50%,总感染率是36.6%和45%。支原体对抗生素敏感性最强的是交沙霉素、美满霉素、强力霉素、克拉霉素,两年相同。2005年对抗生素耐药性最强的是四环素、阿奇霉素、罗红霉素。2008年对抗生素耐药性最强的是氧氟沙星、四环素、司帕沙星、左旋氧氟沙星。结论:2008年感染率和耐药率均高于2005年。交沙霉素、美满霉素、强力霉素、克拉霉素是本地区治疗支原体的首选药物。加强成年男女对支原体相关医学知识的健康教育,降低感染率。根据体外药敏试验选择高效药物足剂量足疗程用药,降低耐药率。 Objective:To analyze the urogenital tract mycoplasma infection and drug sensitivity in Guangzhou in 2005 and 2008. Methods:Mycoplasma cultured and tested for 10 drugs sensitivity for urogenital tract infectious patients in 2005 and 2008. Results:Male mycoplasma infection was 31% in 2005 and 30% in 2008, famale mycoplasma infection was 38.7% in 2005 and 50% in 2008, total infection was 36. 6% in 2005 and 45% in 2008. The most sensitive drugs of mycoplasma in two years were same, they were Josanycin minocycline doxycycline sparfloxacin. The most resistant drug in 2005 were tetracycline azithromycin roxithrom. The most resistant drug in 2008 were ofloxacin tetracycline sparfloxacin levofloxacin. Conclusion:The infection and drug resistance in 2008 were higher than in 2005. Josanycin, minocycline hydrochloride, doxycycline hyelate sparfloxacin were first chosen to cure mycoplasma infection. The healthy education about mycoplasma for adult must be enforced to reduce the infection. According to the drug sensitive test to choose effective drugs to reduce the resistance.
出处 《中国卫生检验杂志》 CAS 2009年第7期1554-1555,共2页 Chinese Journal of Health Laboratory Technology
关键词 泌尿生殖系 支原体感染 药敏 耐药 Urogenital tract Mycoplasma infection Drug sensitivity Drug resistance
  • 相关文献

参考文献5

二级参考文献25

  • 1蔡川川,杨日东,陈绍谦,田广南.广州地区女性泌尿生殖道感染者解脲脲原体体外耐药变化的研究[J].中国皮肤性病学杂志,2005,19(5):279-281. 被引量:11
  • 2马经野,刘全英.泌尿生殖道支原体感染及耐药性研究[J].中国实验诊断学,2007,11(5):644-646. 被引量:19
  • 3Taylor RD. Mycoplasma genitalium-an update[J]. Int J STD AIDSMar, 2002, 13(3): 145 - 151.
  • 4Maeda SI, Tamaki M, Kojima K, et al. Association of mycoplasma genitalium persistence in the urethra with recurrence of nongonococcal urethritis[J]. Sex Transm Dis, 2001,28(8): 472 -476.
  • 5Deriabin DG, Borisov SD. Mikhailenko SV. Mixed urogenital infection in men[J]. Zh Mikrobiol Epidemiol Immunobiol, 2000(2): 103 - t05.
  • 6Taylor RD, Furp MPM. Clinical antibiotic resistance of ureaplasma urealyticum[J]. Pediatr Infect Dis, 2004, 5: S335.
  • 7Xu DX, Chen CW, Hou GW, et al. Determination of mycoplasma by mycoplasma IST kits[J]. Chinese Journal of Dermatology, 1997,20: 3.
  • 8Kenny G E,Hooton T M,Roberts M C,et al.Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method[J].Antimicrob Agents Chemother,1989,(33):103-107.
  • 9Hooper D C.Bacterial topoisomerases,anti-topoisomerases,and antitopoisomerase resistance[J].Clin Infect Dis,1998,(27):54-63.
  • 10Bebear C M,Renaudin H,Charron A,et al.In Vitro activity of trovafloxacin compared to those of five antimicrobials against mycoplasmas including mycoplasma hominis and ureaplasma urealyticum fluoroquinolone-resistant isolates that have been genetically characterized[J].Antimicrob Agents Chemother,2000,44(9):2557-2560.

共引文献116

同被引文献27

引证文献4

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部