摘要
目的了解淮安地区非淋菌性尿道炎(NGU)患者泌尿生殖道解脲脲原体(Uu)和人型支原体(Mh)感染状况以及耐药性。方法对426例患者泌尿生殖道支原体进行分离培养,并采用支原体药敏试剂盒分析其耐药性。结果 426例NGU患者支原体检出269例,总检出率63.1%,其中Uu检出率50.5%;Mh检出率2.1%;Uu、Mh混合型支原体检出率10.6%。女性总检出率65.2%,其中Uu、Mh和混合感染检出率分别是52.5%、1.8%和10.8%;男性支原体总检出率46.81%,Uu、Mh和(Uu+Mh)检出率分别是25.2%、2.3%和8.5%。男性、女性检出率比较,差异有统计学意义(P<0.05)。支原体对强力霉素、交沙霉素、阿奇霉素和克拉霉素较为敏感。结论 NGU患者泌尿生殖道有较高的支原体感染率,且女性总检出率高于男性。支原体体外药物敏感试验可以指导临床泌尿生殖系支原体感染的治疗。
Objective To analyze the infection and drug resistance of nongonococcal urethritis （NGU） patients infected by ureaplasma urealyticum （Uu） and mycoplasma hominis （Mh） in the local area.Methods Mycoplasmas were isolated form 426 cases of NGU and their antibiotic susceptibility were detected with mycoplasma susceptibility test kits.Results Among 426 cases of NGU,269 cases had mycoplasmal infection,the total positive percentage was 63.1%,in which the positive rates of Uu and Mh were 50.5% and 2.1% respectively,and 10.6% cases were infected by both Uu and Mh.With the total positive percentage being 65.2% in female,the positive rates of Uu and Mh were 52.5% and 1.8% respectively,and 10.8% cases were infected by both Uu and Mh.While the total positive percentage was 25.2% in male,in which the positive rates of Uu and Mh were 25.2% and 2.3% respectively,and 8.5% cases were infected by both Uu and Mh.There was significant difference between male and female （P〈0.05）.Josamycin,doxycycline,clarithromycin and azithromycin were of more effection against mycoplasma infection.Conclusion There is a high infection rate of mycoplasma in NGU patients,and the detection rate is higher in female than male.The drug sensitivity test in vitro of mycolasma can guide the clinical treatment of urogenital mycoplasma infection.
出处
《检验医学与临床》
CAS
2010年第17期1833-1834,共2页
Laboratory Medicine and Clinic
