摘要
动脉粥样硬化(AS)是引起心脑血管疾病的主要原因。然而,AS的发展过程有免疫反应参与。其中,有巨噬性粒细胞为主要效应细胞的天然免疫反应和淋巴细胞为主要效应细胞的获得性免疫方面。快速启动的天然免疫,包括吞噬性细胞、补体和炎细胞因子,都促进AS的形成。另外,获得性免疫相关的T细胞、抗体、免疫调节性细胞因子对于AS病变的活动、进展亦发挥重要的调节作用。本文综述了近几年来,通心络胶囊治疗AS实验研究进展,为临床应用提供参考。
Atherosclerosis （AS） is a chronic disease that causes artery walls to thicken and become to less elastic. The result can lead to heart attacks, stroke and other serious cardiovascular illnesses, cerebrevascular disease. However, immune mechanisms have been suggested to play a key role in the whole course development of AS. Which are controversy exists regarding the participation of innate immunity involving macrophages and antigen-specific acquired immunity involving lymphocytes. Rapidly mobilized arms of innate immunity, including phagocytic leukocytes, complement, and preinflammatory cytokines, contribute to AS. In addition, adaptive immunity, with its T cells, antibodies, and immunoregulatory cytokines, pewerfully modulates disease activity and progression. Now this article summarizes the remarkable results in research advancement of treated effect in experiment of AS by using Tongxinluo capsule, its reviewed in recent several years. Which should be provided clinical applied refer to its.
出处
《中国民族民间医药》
2009年第13期63-65,共3页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
通心络胶囊
动脉粥样硬化
实验
综述
Tongxinluo capsule
Atherescleresis
Experiment
Review
