摘要
目的:观察中国被毛孢发酵物对亚健康大鼠血生化等指标的改善作用。方法:连续96h的快速动眼相睡眠剥夺(REMSD)造成亚健康大鼠模型,灌胃给予中国被毛孢发酵物后观察亚健康大鼠的体重、脏器指数、血pH值、血氧分压(PaO2)、氧饱和度(SO2%)、肝肾功能、超氧化物歧化酶(SOD)和丙二醛(MDA)等指标。结果:中国被毛孢发酵物能不同程度的改善睡眠剥夺大鼠亚健康体征,增加大鼠体重,调节血液酸碱度,提高血氧分压和饱和度,改善肝肾功能和自由基代谢异常等;结论:中国被毛孢发酵物具有较好的改善亚健康状态。
Object：To investigate the effect of Hirsutella sinensis strain fermentation on sub-health rats with sleep- deprivation. Methods： Continuous sleep deprivation of 96 hours caused sub-health in rats. After Hirsutella sinensis strain fermentation administration, the rats are detected those index, such as weight, organ index, blood pH, PaO2, SO2 %, SOD and MDA. Results： The experimental result indicate that fermentation of Hirsutella sinensis strain can improve physical sign, gain weight, regulate blood pH, enhance PaO2 and SO2 % , improve hepatic and renal function, retrieve free radical metabolism in sub-health rats. Conclusion： Hirsutella sinensis strain fermentation is benefit to sub-health rats.
出处
《中国实验方剂学杂志》
CAS
北大核心
2009年第6期59-62,共4页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
中国被毛孢发酵物
亚健康
睡眠剥夺
fermentation of Hirsutella sinertsis strain
sub-health
sleep deprivation
