摘要
瘢痕组织是人体创伤修复过程中的一种病理性产物,是成纤维细胞——胶原蛋白——细胞因子三者过度失衡,使细胞外基质增生而形成瘢痕,从而导致人体外形的破坏和功能障碍。目前,虽然治疗瘢痕的方法和药物很多,但治疗效果均不甚理想。本文根据Lee等报道的有关钙离子拈抗剂治疗瘢痕的资料,对其作用机理的临床疗效作一综述,为寻求治疗瘢痕提供一条思路。
Scar tissues are the pathological product caused by the process of human body＇ s wound healing repair. It is a result of imbalance among fibroblasts, collagen and cytokine, that causes extracellular matrix hyperplasia and scar formation, finally results in human body＇ s appears destroy and dysfunction. Now, although a lot of methods and drugs were claimed to treat scar, no ideal results were obtained. Based on Lee＇ s reports, scar treatment with calcium antagonist was reviewed in this paper, including the mechanism and clinical effect, so as to try approaching a way of scar treatment.
出处
《中国烧伤创疡杂志》
2009年第2期99-103,共5页
The Chinese Journal of Burns Wounds & Surface Ulcers
