摘要
目的了解本院大肠埃希氏菌（Escherichia coli,E.coli）的临床分布情况及对抗菌药物的敏感性。方法对本院2006年1月-2007年8月检出的951例E.coli用法国生物梅里埃API药敏系统进行耐药性分析。结果E.coli在临床标本中检出的分布百分比以尿液标本最常见（27.2%）,其余依次是痰液（26.1%）和血液（20.5%）。体外试验对头孢菌素、庆大霉素、复方磺胺甲噁唑、环丙沙星有较高的耐药性,对亚胺培南、美罗培南和阿米卡星较敏感。结论大肠埃希氏菌存在比较严重的耐药情况。临床应尽早进行细菌培养和对抗菌药物的耐药性监测,以期指导临床合理用药。
Objective To investigate the distributions and drug resistance of Escherichia coli detected in our hospital. Methods Distributing conditions of 951 strains Escherichia coli among clinical samples isolated by routine bacterium culture in our hospital from Jan 2006 to Aug 2007 were studied retrospectively,drug resistances were explored by API half-automicroscan system. Results Separation rates of Escherichia coli in clinical samples such as urine,sputum,blood were higher,which were 27.2%,26.1% and 20.5% respectively.These strains were susceptible only to imipenem,meropenem and amikacin,and the rate of drug-resistance to other antibiotics were all more than 50.0%. Conclusions Escherichia coli has high resistance to a lot of antibiotics.Bacteria culturing and monitoring their resistance to antibiotics should be applied early in clinical jobs to guide reasonable drug prescription and control nosocomial infection effectively.
出处
《南华大学学报（医学版）》
2008年第6期801-802,805,共3页
Journal of Nanhua University(Medical Edition)
关键词
大肠埃希氏菌
抗菌药物
耐药性
Escherichia coli
antibiotics
antibiotic resistance
