摘要
胃电刺激(GES)是将类似于心脏起搏的电子脉冲发生器和一根双极导线植入胃壁肌层,然后激活外源性电脉冲刺激来干扰正常的胃电-运动功能。近年来,GES被尝试应用于治疗肥胖。它的优点在于不改变胃肠道正常解剖结构,不影响肠道吸收功能,而是通过电刺激引起早饱、抑制食欲从而减少摄食。研究显示,GES可引起体质量明显下降,并且是最安全的方法。本文将对自20世纪90年代中期开始的临床试验予以综述,并对其发展前景予以展望。
Gastric electrical stimulation （GES） is a kind of gastric pacing （ including the impulse generator and the bipolar leads） used for destroying the normal gastric electrical-mechanical function. GES has been used as one method of treatment for obesity recently. The advantage of GES is to decrease food intake by inducing early-satiety and inhibiting appetite without changing the anatomy of gastrointestinal tract while keeping the function of digestion and absorption. Up to now, many clinical studies have showed that GES could induce significant weight loss without obvious side-effect. This paper reviews these researches in order to encourage deeper investigations.
出处
《医学综述》
2008年第23期3543-3545,共3页
Medical Recapitulate
关键词
胃电刺激
肥胖
体质量下降
Gastric electrical stimulation
Obesity
Weight loss
