期刊文献+

原发性病理性十二指肠胃反流患者胃黏膜细胞增殖与凋亡的研究 被引量:3

Apoptosis and proliferation of gastric mucosal cells in patients with primary pathological duodenogastric reflux
暂未订购
导出
摘要 目的:研究原发性病理性十二指肠胃反流患者胃黏膜组织中的凋亡细胞、增殖细胞,探讨原发性病理性十二指肠胃反流的发病机制。方法:应用脱氧核糖核酸转移酶介导的缺口末端标记技术和免疫组化方法分析86例原发性病理性十二指肠胃反流和42例正常对照胃黏膜细胞凋亡及增殖细胞核抗原的表达。结果:原发性病理性十二指肠胃反流组凋亡指数和增殖指数均显著高于正常对照组(P<0.05),Hp阳性和Hp阴性亚组之间凋亡指数和增殖指数无显著性差异(P>0.05)。结论:胃黏膜细胞增殖与凋亡增强可能是原发性病理性十二指肠胃反流的发病机制之一,Hp感染未加重原发性病理性十二指肠胃反流所致胃黏膜细胞凋亡和增殖反应。
出处 《第二军医大学学报》 CAS CSCD 北大核心 2008年第11期1412-1414,共3页 Academic Journal of Second Military Medical University
基金 河北省科学技术研究与发展指导计划(072761861)~~
  • 相关文献

参考文献4

二级参考文献25

  • 1Iwanga T,Gastroenterology,1993年,105卷,1089页
  • 2Malfertheiner P, Megraud F, O'Morain C, et al. European Helicobacter Pylori Study Group(EHPSG). Current concepts in the management of Helicobacter pylori infection-the Maastricht 2-2000 Consensus Report. Aliment Pharmacol Ther, 2002,16:167-180.
  • 3Yuzuru Sugiyama,Hiroyasu Kobori,Kenichi Hakamada,Dai Seito,Mutsuo Sasaki.Altered Bile Composition in the Gallbladder and Common Bile Duct of Patients with Anomalous Pancreaticobiliary Ductal Junction[J].World Journal of Surgery.2000(1)
  • 4David Armstrong MA, MRCP (UK),Edward R. C. Rytina MD,Gerard M. Murphy PhD,Professor R. Hermon Dowling MD, FRCP.Gastric mucosal toxicity of duodenal juice constituents in the rat[J].Digestive Diseases and Sciences.1994(2)
  • 5Edgar Deinlein,Helmut Schmidt,Jürgen-Ferdinand Riemann,Rolf Gr??el-Pietrusky,Otto Paul Hornstein.DNA flow cytometric measurements in inflammatory and malignant human gastric lesions[J].Virchows Archiv A Pathological Anatomy and Histopathology.1983(2)
  • 6Peter Langhans M.D.,Ralph A. Heger M.D.,J. Hohenstein,Werner Schlake M.D,Hermann Bünte M.D.Operation-sequel carcinoma of the stomach. Experimental studies of surgical techniques with or without resection[J].World Journal of Surgery.1981(4)
  • 7Dewer P,Dixon MF,Jonston D.Bile reflex and degree of gastritis in patients with gastric ulcer:before and after operation[].Journal of Surgical Research.1984
  • 8Pointner R,Schwab G,Konigstrainer A.Gastric stump cancer:etiopathological and clinical aspects[].Endoscopy.1989
  • 9Teodori L,Capurso L,Cordelli E.Cytometrically determined relative DNA content as an indicater of neoplasia in gastric lesions[].Cytometry.1984
  • 10Reed PI.Smith PLR,Haines K.Gaatric juice N-nitrosamines in health and gastroduodenal disease[].The Lancet.1980

共引文献518

同被引文献27

引证文献3

二级引证文献20

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部