摘要
目的通过分析原发性病理性十二指肠胃反流(DGR)患者胆汁反流程度与胃肠传输时间以及肛门直肠动力学特征之间的关系,探讨原发性病理性DGR致病因素。方法对58例原发性病理性DGR患者和21例健康者(对照组)进行胃肠传输时间和肛门直肠测压检测,并计算DGR患者排便症状评分。结果①DGR组胃肠传输时间(gastrointestinal transit time,GITT)较正常对照组延长[(40.62±10.11)h vs(26.57±8.54)h,P<0.05],钡条残留率较对照组高[(38.51±0.74)%vs(15.28±0.67)%,P<0.05];高反流组GITT较低反流组延长[(48.62±10.41)h vs(35.35±10.05)h,P<0.05],钡条存留率较低反流组高[(50.74±0.74)%vs(29.56±0.68)%,P<0.05];②DGR组与正常对照组比较,肛门直肠压力及感觉功能无显著性差异;③DGR患者排便症状各组评分与对照组比较差异有统计学意义;低反流组的排便频率、排便时间与高反流组比较差异有统计学意义,其余各症状评分较高反流组无差异。结论原发性病理性DGR患者存在下消化道运动功能障碍,可能存在共同的病理生理基础。
To study the pathological factors by analyzing the relationship among the bile reflux degrees, gastrointestinal transit time and anorectal motility spectrum in primary pathological DGR patients. Methods Gastrointestinal transit time and anorectal manometry were detected in 58 cases of primary pathological DGR patients and 21 healthy persons （control group）. Results ① GITT in patients of primary pathological DGR was longer than that in the control group [ （40.62 ± 10.11 ） h vs （26.57 ± 8.54） h, P 〈 0.05 ]. Average barium bar left rate was higher than that in the control group [ （38.51 ±0.74）% vs （15.28 ±0.67）% , P 〈0.05]. GITT in the patients of the high-reflux group was longer than the low-reflux group [ （48.62 ± 10.41 ）h vs （35.35 ± 10.05 ）h,P 〈 O. 05 ], and average barium bar left rate was higher than that in the low-reflux group [（50.74 ±0.74）% vs （29.56±0.68）%,P〈0.05]. ② There were no difference of anorectal motility and rectal visceral perception to balloon distention between patients with primary pathological DGR and the control group ;③ The symptom scores of constipation in DGR patients had significantly difference compared with the control group, the scores of defecate frequence and time in the high-reflux patients were better than those in the low-reflux group, other symptom scores had no differences in high-reflux group. Conclusion The patients with primary pathological DGR have abnormal lower gastroenteral motility dysfunction, which may be same pathophysiological mechanism.
出处
《胃肠病学和肝病学杂志》
CAS
2013年第1期53-56,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
原发性病理性十二指肠胃反流
胃内胆汁监测
胃肠传输时间
肛门直肠测压
功能性胃肠病
Primary pathological duodenogastric reflux
Monitoring of bile reflux
Gastrointestinal transit time
Anorectal manometry
Functional gastrointestinal disorder
