摘要
用长时间甲苯胺蓝等组织化学方法,研究了性激系对大鼠胸腺中肥大细胞数量及分布的影响。结果表明:接受雌二醇或睾酮处理的大鼠胸腺中肥大细胞数量显著减少(P<0.01);阉割则能使胸腺中肥大细胞显著增加(P<0.01)。提示减少胸腺中肥大细胞数可能是性激素影响机体免疫功能的途径之一。文内还讨论了性激素对胸腺的影响的机制等问题。
The effects of sex steroids (estradiol and testosterone) on the distribution and the total number of mast cells in rat thymus were investigated. The mast cells of the thymus were stained with 4 methods(toluidine blue, long toluidine blue, alcian blue-safranin, Grimelious siliver method).The results showed that estradiol and testosterone treatment brought about the decrease in total mumber of mast cells, while castration the increase in the total number of mast cells. The results suggest that the decrease in the total number of mast cells may be the effect of the sex steroids on the immune system.
出处
《解剖学杂志》
CAS
CSCD
北大核心
1997年第5期478-481,共4页
Chinese Journal of Anatomy
关键词
胸腺
肥大细胞
性激素
数量
分布
thymus
mast cell
sex steroid
estradiol
testosterone
