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IL-6对约氏疟原虫配子体感染力的影响 被引量:1

THE EFFECT OF RHU INTERLEUKIN 6 ONTHE INFFECTIVITY OF PLASMODIUM YOELII GAMETOCYTES
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摘要 在血传感染约氏疟原虫后第54h、70h分别皮下注射1000U人IL-6或血传感染后第70h静注2000U人IL-6,在第72h分别被斯氏按蚊吸血,吸血后第7d解剖蚊胃,观察其感染率、感染度。结果表明:按不同途径、不同时间给感染小鼠注入IL-62000U,与对照组相比,对按蚊的感染率和感染度无明显影响。 The effect of IL6 on infectivity of P. yoelii gametocytes was investigated. The mice infected with P. yoelii were treated with 2 000U rhu IL6. Mice were dicided into three groups. One was treated with 1 000U rhu IL6 on the 54 h and 70 h ID following the infective blood meal respectively; The second was treated with 2 000U rhu IL6 on the 70 h IV following the infective blood meal. The third was untreated as a control. Midguts were dissected 7 d following infective blood meal. Oocyst rates(the percentage of mosquitoes exhibiting oocysts) and the number of oocysts per mosquito were determined. These results indicated that there were no significant differences among three groups in the oocyst rates and the number of oocysts.
出处 《中国寄生虫病防治杂志》 CSCD 1997年第4期274-276,共3页 Chinese Journal of Parasitic Disease Control
基金 国家自然科学基金
关键词 IL-6 约氏疟原虫 配子体 感染力 疟疾 IL6, Plasmodium yoelii,gametocyte,infectivity
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