摘要
对16例肝癌病人外周血及脾静脉血T淋巴细胞亚群检测结果：1）肝癌患者较对照组外周血CD+3、CD+4细胞及CD4／CD8比值降低，CD+8细胞升高。2）肝癌患者脾静脉血较外周血CD+3、CD+4阳性细胞、CD4／CD8比例明显降低，CD+8显著升高。认为随着病程进展，脾脏不但不起正性免疫作用，反而转向负性免疫状态。同时，还对肝癌患者的脾脏手术问题进行了讨论。
T-lymphocyte subsets of peripheral blood (PBL) and splenicvenous blood (SVL) were determined on 16 patients with HCC. The resultsshowed that in cancer patients the count of CD, CD cells, and the ratio of CD4/CD8 declined, while the value of CD cells increased in PBL than those in the control group. In HCC patients the count of CD, CD cells and the ratio of CD4/CD8cells in SVL were significantly lower than those in the PBL, but the CD cellscount was markedly higher than that in PBL. It suggests that the spleen exerts notonly no immunologic function with the progression of cancer, but rather a negativeone.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1997年第10期751-751,共1页
Chinese Journal of Clinical Oncology
关键词
脾脏免疫状态
T淋巴细胞亚群
肝肿瘤
Hepatocellular carcinoma (HCC) Immune status T-lymphocyte subsets Spleen
