摘要
目的:临床观察采用肝动脉栓塞化疗联合部分脾动脉栓塞治疗原发性肝癌合并脾功能亢进的疗效。方法:住院原发性肝癌伴肝硬化脾功能亢进患者34例,采用经皮穿刺肝动脉插管化疗栓塞及脾动脉部分栓塞治疗。治疗前后行检测肝功能、免疫指标、外周血及B超、CT等。结果:术后CT随访显示肝脏瘤体缩小24例,占70.58% (24/ 34),其中缩小50% 以上者13例,2例治疗后行二期手术切除;脾脏栓塞后CT复查缩小,最多34.7% ,最少20.6% 。AFP治疗后有不同程度下降.有23例治疗后肝功能改善。免疫指标治疗前后无大变化。动态监测治疗后外周血象,WBC、RBC、PT均有提高,其中PT治疗后明显升高(P<0.01)。结论:肝动脉及部分脾动脉栓塞伴化疗可使肝肿瘤缩小.脾功能亢进缓解,是中晚期肝癌伴肝硬化脾亢的有效洽疗手段之一。
Purpose: To observe therapeutic effectiveness of combined embolism of hepatic artery and partial splenic artery in the treating primary liver cancer concurred hypersplenism. Method: We choosed 34 in-patients of primary liver cancer concurred cirrhosis and hypersplenism. They were given percutaneous puncture of liver artery heptic artery and partial splenic artery embolism combined with chemotherapy. We detected liver function, immune index, blood routine, B-US and CT. Result: CT result following up operation showed 24 cases' liver tumor shrinked, occupied 70.58% (24/34). Of them 13 cases shrinked more than 50% . 2 cases had secondary operation after treatment. After embolism, spleen shrinked by checking CT. The most one was 34.7% and the least one was 20.0 % . AFP declined with different effect. 23 cases liver function developed. Immune index had no change before and after treatment. WBC, RBC, and PT all developed by dynamic observation of blood routine. Especially PT elevated significantly after treatment (P <0.01). Conclusion: Embolizing liver artery and partial splenic artery combined with chemotherapy can shrink liver, tumor, remit, remit hypersplenism. So it was an effective method to treat medium and late stage liver cancer.
出处
《临床消化病杂志》
1999年第4期149-150,155,共3页
Chinese Journal of Clinical Gastroenterology
关键词
原发性
肝癌
脾功能亢进
栓塞化疗
治疗
Primary liver cancer Hypersplenism Embolism Chemotherapy
