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不同浓度的左旋布比卡因用于可行走式分娩镇痛 被引量：6

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摘要 目的探讨不同低浓度左旋布比卡因复合舒芬太尼硬膜外自控镇痛用于产妇可行走式分娩镇痛的可行性，寻找左旋布比卡因的最佳有效浓度。方法60例ASAⅠ～Ⅱ级初产妇随机分为3组：Ⅰ组镇痛配方为0．075％左旋布比卡因加0．2μg／ml舒芬太尼；Ⅱ组为0．1％左旋布比卡因加0．2μg／ml舒芬太尼；Ⅲ组为0．15％左旋布比卡因加0．2μg／ml舒芬太尼。记录镇痛起效时间、PCA次数、VAS评分、运动神经阻滞评分、分娩时间和方式、产妇满意度和新生儿Apgar评分。结果Ⅰ组起效时间、PCA次数、用药量显著高于Ⅱ组与Ⅲ组（P〈0．01）；Ⅱ组与Ⅲ组镇痛后的VAS评分明显低于Ⅰ组，镇痛满意率也显著高于Ⅰ组（P〈0．01）。Ⅲ组与Ⅱ组相比，镇痛效果、分娩时间与方式差异无统计学意义（P〉0．05），但出现轻度运动神经阻滞的比例Ⅲ组明显高于Ⅱ组（P〈0．05）。结论0．1％左旋布比卡因复合0．2μg／ml舒芬太尼既能提供良好的镇痛且对下肢运动神经影响轻微，是可行走式分娩镇痛较为理想的一种用药方案。
作者 韩伟光 杨承祥
机构地区 广东省广州市番禺区何贤纪念医院
出处 《中国医师杂志》 CAS 2008年第2期258-260,共3页 Journal of Chinese Physician
关键词 布比卡因/投药和剂量 镇痛 产科
分类号 R614 [医药卫生—麻醉学] R714.3 [医药卫生—妇产科学]
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参考文献5

  • 1张黄丽,刘怀琼,葛衡江.左旋布比卡因的药理学及临床应用[J].武警医学,2004,15(7):542-544. 被引量：10
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二级参考文献29

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共引文献9

同被引文献35

引证文献6

二级引证文献34

中国医师杂志
2008年 第2期

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