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bFGF重组腺病毒转染骨髓间质干细胞促进VEGF的表达 被引量：3

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摘要 目的探讨碱性成纤维生长因子(bFGF)重组腺病毒转染骨髓间质干细胞(MSCs)促进VEGF的表达。方法采用酶联免疫吸附(ELISA)法对转染bFGF重组腺病毒的MSCs实验用小型猪急性心梗模型血清中VEGF含量进行测定。结果细胞移植后即刻组Ⅰ与组ⅡVEGF含量无统计学意义(P>0.05),移植后第1w两者比较就有显著差异(P<0.01),而且组ⅠVEGF含量达高峰,第2w、第4w组ⅠVEGF含量与组Ⅱ比较差异仍有统计学意义(P<0.05)。结论bFGF重组腺病毒转染骨髓间质干细胞促进VEGF的表达。
作者 李树岩 回学军 纪磊 艾永顺 张文琪 李雷阳
机构地区 吉林大学第二医院心内科
出处 《中国老年学杂志》 CAS CSCD 北大核心 2007年第22期2171-2173,共3页 Chinese Journal of Gerontology
基金 吉林省科技厅科研基金资助(20037004)
关键词 碱性成纤维生长因子 血管内皮牛长因子 骨髓间质干细胞
分类号 R542.22 [医药卫生—心血管疾病] R457.7 [医药卫生—治疗学]
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共引文献41

同被引文献50

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引证文献3

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中国老年学杂志
2007年 第22期

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