摘要
应用鼠伤寒沙门氏菌株 TA98及其新的衍生菌株 YG1021和 YG1024,对液化石油气燃烧颗粒物的丙酮提取物进行了致突变研究,结果显示,提取物对三菌株均具有明显的直接和间接致突变作用,对 YG 菌株的回变作用远高于对 TA98的回变作用,表明颗粒物中不仅含有多环芳烃类的间接致突变物,而且还含有直接致突变的硝基多环芳烃。提示对液化石油气燃烧颗粒物的潜在致癌性座予以高度重视。
The mutagenicity of acetone extract of liquefied petroleum gas(LPG) combustion particulates was studied with Salmonella typhimurium TA98 and two of its new constructed derivatives strains,YG1021 and YG1024.The results showed that acetone extract of the particulates was direct and indirect significant mutagens in the 3 strains.The reversion of YGstrain was far higher then that of TA98.These suggested that the particulates contain both some indrect mutagenic polyaromatic hydrocarbons (PAHs)and direct mutagenic nitrated polyaromatic hydrocarbons(NO_2-PAHs).The potential carcinogenicity of LPG combustion particulates should be valued seriously.
出处
《承德医学院学报》
1997年第2期93-96,共4页
Journal of Chengde Medical University
基金
国家自然科学基金
关键词
液化石油气
燃烧产物
致突变性
硝基多环芳烃
liquefied petroleum gas
combustion product
mutagenicity
nitrated polyaromatic hydrocarbons
Ames test
