摘要
配合加药含铜宫内节育器的发展,主要应用可以测出铜的瞬时腐蚀速度的腐蚀电化学极化电阻技术,结合XRD和SEM方法,研究了消炎痛对模拟宫腔液中铜腐蚀的影响。结果表明,不控制介质pH情况下,消炎痛使铜的腐蚀速率略有上升;在调节溶液pH大体恒定的情况下,消炎痛基本上不影响铜的腐蚀速率。使用缓释消炎痛硅橡胶的试验结果与直接加消炎痛药粉的结果基本一致。铜丝的腐蚀速率略大于铜管。XRD和SEM检测表明,在模拟宫腔液中,无论加药与否,铜的表面上都只生成Cu_2O,不过,消炎痛使Cu_2O生成的量多且致密。
As a supplemental study of indomethacin-releas-ing copper-bearing intraurerine device (Cu-IUD) , the effects of indomethacin on copper corrosion in simulated uterine fluid were studied by electrochemical polarization resistance technique, which can measure the instant corrosion rate of copper,and by XRD and SEM methods. The experiments indicated that in the presence of indomethacin powder in simulated uterine fluid.it slightly increased the corrosion rate of copper if pH of the fluid was not under control,and did not affect the corrosion rate. if pH was adjusted to a constant level. The corrosion rate of copper wire was a little greater than that of copper tube. The experimental results of silica rubber releasing-indomethacin was basically the same as that with indomethacin powder. The results of XRD and SEM showed that indomethacin did not affect the properties of formed on copper, but increased the resultant amounts of Cu2O.
出处
《中国计划生育学杂志》
1997年第2期74-78,共5页
Chinese Journal of Family Planning
基金
国家计划生育委员会科研项目
得到国家计划生育药具重点实验室资助(资助号:96-13-1)
得到腐蚀与防护国家重点实验室资助
关键词
宫内节育器
消炎痛
铜腐蚀
IUD Indomethacin Copper corrosion Polarization resistance method
