摘要
目的:为深入开展ADR监测工作提供依据。方法:下载2006年深圳市各单位上报的且经省中心评价的ADR报告表,对有关数据进行进行频数分析;以用药时间、ADR发生时间、转归时间来评价ADR过程记录的完整性;采用对比方式进行关联性评价。结果:3 303份ADR报告涉及的药品有19类,共465种。抗微生物药、中成药品种数及其所致ADR例数位居前列;ADR累及的器官或系统主要为皮肤及其附件,其次为消化系统;静脉滴注导致的ADR例次最多;绝大多数ADR转归良好;新的、严重的ADR上报较少。结论:应加强上报人员的培训工作,增强ADR呈报意识和责任感,以提高ADR报告质量;应对医师的处方行为进行适当干预,以减少ADR的发生。
OBJECTIVE：To analyze the basic data of adverse drug reactions（ADR） and assess the quality of ADR reports submitted in 2006 in Shenzhen, and to provide bases for ADR monitoring.METHOD： The electronic forms of ADR cases reported in 2006 by different units in Shenzhen that had been subjected to the evaluation of Guangdong provincial center were downloaded, and the related data were subjected to frequency analysis. The three time points（ duration of medication, onset time of ADR, turnover time） were used to evaluate the integrity of ADR process recording, and the relevance was evaluated by means of contrast. RESULTS： 19 drug categories and total 465 kinds of medicines were involved in 3 303 ADR cases .The categories of antimicrobials and Chinese herbal preparations and ADR cases induced by these drugs ranked at the first and second among all the drugs.The lesions of ADR involved primarily skin and its accessories, followed by gastrointestinal system. Most ADR cases were caused thorough intravenous route of administration .The majority ADR cases had a favorable turnover.New and severe ADR reports were few.The qualities of most reports were poor.CONCLUSION： The training program for ADR reporters should be strengthened; ADR reporters＇ reporting awareness and responsibility should be strengthened to enhance ADR re- porting quality,and physicians＇ prescribing behavior should be intervened properly so as to reduce the incidence of ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2007年第26期2052-2054,共3页
China Pharmacy
关键词
药品不良反应
统计
回顾性分析
质量评估
Adverse drug reaction
Statistics
Retrospective analysis
Quality assessment
