4Morike K,Schwab M,Klotz U. Use of aminoglycosides in elderly patients:pharmacokinetic and clinical considerations [J ]. Drugs Aging. 1997,10 (4):259 ～ 277.
5Nicolau DP, Freeman CD, Belliveau PP, et al. Experience with a once -daily aminoglycoside program administered to 2184 adult patients[J]. Antimicrob Agents Chemother, 1995,39: (3)650 ～ 655.
